dextro-looped transposition of the great arteries
Findings
No curated finding names dextro-looped transposition of the great arteries yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Congenitally uncorrected transposition of the great arteries (congenitally uncorrected TGA), also referred to as complete transposition, is a congenital cardiac malformation characterized by atrioventricular concordance and ventriculoarterial (VA) discordance.
Definition from the Mondo Disease Ontology (MONDO:0019443), read 2026-09-29. CC BY 4.0.
Features
31 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal ventriculoarterial connectionHPOHP:0011563
- Very frequent (80% to 99% of cases)
- Abnormality of blood circulationHPOHP:0011028
- Very frequent (80% to 99% of cases)
- Cardiac shuntHPOHP:0001693
- Very frequent (80% to 99% of cases)
- CyanosisHPOHP:0000961
- Very frequent (80% to 99% of cases)
- Heart murmurHPOHP:0030148
- Very frequent (80% to 99% of cases)
- HypoxemiaHPOHP:0012418
- Very frequent (80% to 99% of cases)
- TachycardiaHPOHP:0001649
- Very frequent (80% to 99% of cases)
- Abnormal aortic arch morphologyHPOHP:0012303
- Frequent (30% to 79% of cases)
- Abnormal coronary artery morphologyHPOHP:0006704
- Frequent (30% to 79% of cases)
- Abnormal mitral valve morphologyHPOHP:0001633
- Frequent (30% to 79% of cases)
- Abnormal pulmonary valve morphologyHPOHP:0001641
- Frequent (30% to 79% of cases)
- Abnormal QRS complexHPOHP:0025074
- Frequent (30% to 79% of cases)
Show the remaining 19
- Anomalous pulmonary venous returnHPOHP:0010772
- Frequent (30% to 79% of cases)
- Atrial septal defectHPOHP:0001631
- Frequent (30% to 79% of cases)
- Biventricular hypertrophyHPOHP:0200128
- Frequent (30% to 79% of cases)
- CardiomegalyHPOHP:0001640
- Frequent (30% to 79% of cases)
- Congestive heart failureHPOHP:0001635
- Frequent (30% to 79% of cases)
- Dextrotransposition of the great arteriesHPO · MondoHP:0031348
- Frequent (30% to 79% of cases)
Where it sits
Other names
5 names
Resolves to: dextro-looped transposition of the great arteries
- Also called
- congenitally uncorrected transposition of the great arteriescongenitally uncorrected transposition of the great vesselsDTGAisolated ventriculoarterial discordanceventriculoarterial discordance with atrioventricular concordance