deafness-infertility syndrome
MONDO:0012621Mondo
Findings
No curated finding names deafness-infertility syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Deafness-infertility syndrome (DIS) is a very rare syndrome associating sensorineural deafness and male infertility.
Definition from the Mondo Disease Ontology (MONDO:0012621), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Congenital onset
HPO, annotations 2026-09-02
Features
9 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal sperm head morphologyHPOHP:0012865
- 3 of 3 reported patients
- Abnormal sperm tail morphologyHPOHP:0012868
- 3 of 3 reported patients
- Abnormal spermatogenesisHPOHP:0008669
- 3 of 3 reported patients
- Bilateral sensorineural hearing impairmentHPOHP:0008619
- 10 of 10 reported patients · Congenital onset
- Male infertilityHPOHP:0003251
- 3 of 3 reported patients · Young adult onset
- Very frequent (80% to 99% of cases)
- Reduced sperm motilityHPOHP:0012207
- 3 of 3 reported patients
Where it sits
Other names
2 names
Resolves to: deafness-infertility syndrome
- Also called
- deafness and male infertilityDIS