cytokine release syndrome
MONDO:0600008Mondo
Findings
No curated finding names cytokine release syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A syndrome that occurs after therapeutic infusion of antibodies into the blood and is characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath. It is caused by the release of cytokines from the cells that are targeted by the antibodies. Most patients experience a mild to moderate reaction; however, the reaction may be severe and life-threatening.
Definition from the Mondo Disease Ontology (MONDO:0600008), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
3 names
Resolves to: cytokine release syndrome
- Also called
- CRScytokine stormcytokine-associated toxicity