cyclic vomiting syndrome
Findings
No curated finding names cyclic vomiting syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare functional disorder characterized by recurrent, stereotypical episodes of severe nausea and vomiting separated by symptom-free intervals. Episodes are often accompanied by pallor, lethargy, and abdominal pain. The condition shows a strong association with migraine headaches and may have maternal inheritance patterns suggestive of mitochondrial involvement.
Definition from the Mondo Disease Ontology (MONDO:0010778), read 2026-09-29. CC BY 4.0.
- Inheritance
- Mitochondrial inheritance
- Onset and course
- Childhood onset
HPO, annotations 2026-09-02
Features
9 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- VomitingHPOHP:0002013
- 4 of 4 reported patients
- Abdominal painMondoHP:0002027
- AnxietyMondoHP:0000739
- HeadacheMondoHP:0002315
- IrritabilityMondoHP:0000737
- LethargyMondoHP:0001254
- MigraineHPOHP:0002076
- Nausea and vomitingMondoHP:0002017
- PallorMondo
Where it sits
- A kind of