cyanide-induced parkinsonism
Findings
No curated finding names cyanide-induced parkinsonism yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Cyanide-induced parkinsonism is a rare parkinsonian syndrome due to intoxication which develops in individuals surviving an acute cyanide intoxication episode or due to chronic exposure to small cyanide doses. It presents several weeks after acute exposure with progressive typical clinical features of parkinsonism including bradykinesia, rigidity, dystonia, hypomimia, hypokinetic dysarthria, postural instability and retropulsion but no resting or postural tremor. Brain MRI reveals bilateral lesions in the pallidum, posterior putamen, substantia nigra, subthalamic nucleus, temporal and occipital cortex, and cerebellum.
Definition from the Mondo Disease Ontology (MONDO:0017640), read 2026-09-29. CC BY 4.0.
Features
20 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal skin morphologyHPOHP:0011121
- Frequent (30% to 79% of cases)
- Abnormal speech patternHPOHP:0002167
- Frequent (30% to 79% of cases)
- AnarthriaHPOHP:0002425
- Frequent (30% to 79% of cases)
- ApathyHPOHP:0000741
- Frequent (30% to 79% of cases)
- BradykinesiaHPOHP:0002067
- Frequent (30% to 79% of cases)
- Cerebral cortical atrophyHPOHP:0002120
- Frequent (30% to 79% of cases)
- Decreased facial expressionHPO
Show the remaining 8
- Mask-like faciesHPOHP:0000298
- Frequent (30% to 79% of cases)
- ParkinsonismHPOHP:0001300
- Frequent (30% to 79% of cases)
- Postural instabilityHPOHP:0002172
- Frequent (30% to 79% of cases)
- Resting tremorHPOHP:0002322
- Frequent (30% to 79% of cases)
- RigidityHPOHP:0002063
- Frequent (30% to 79% of cases)
- Short stepped shuffling gaitHPOHP:0007311
- Frequent (30% to 79% of cases)
Where it sits
- A kind of