cutaneous leukocytoclastic angiitis
Findings
No curated finding names cutaneous leukocytoclastic angiitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Cutaneous leukocytoclastic angiitis is a small-vessel vasculitis presenting with palpable purpura and urticarial lesions which predate the purpuric lesions most frequently observed on the legs. Systemic symptoms including fever, cough, hemoptysis, sinusitis, arthralgia, arthritis, myalgia, abdominal pain, diarrhea, hematochezia, paresthesia, weakness, and hematuria may be observed. Skin biopsy reveals exudates rich in neutrophils, endothelial damage, fibrin deposition, and leukocytoclasis in postcapillary venules of small vessels. Cutaneous leukocytoclastic angiitis can be idiopathic (in up to 50% of cases) or secondary to infections, medications (such as antituberculosis medication), collagen vascular diseases, or neoplasms.
Definition from the Mondo Disease Ontology (MONDO:0019509), read 2026-09-29. CC BY 4.0.
Features
14 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Cutis marmorataHPOHP:0000965
- Very frequent (80% to 99% of cases)
- ErythemaHPOHP:0010783
- Very frequent (80% to 99% of cases)
- FeverHPOHP:0001945
- Very frequent (80% to 99% of cases)
- GangreneHPOHP:0100758
- Very frequent (80% to 99% of cases)
- MyalgiaHPOHP:0003326
- Very frequent (80% to 99% of cases)
- PapuleHPOHP:0200034
- Very frequent (80% to 99% of cases)
- PurpuraHPO
Show the remaining 2
- Abnormal oral cavity morphologyHPOHP:0000163
- Occasional (5% to 29% of cases)
- Subcutaneous noduleHPOHP:0001482
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
5 names
Resolves to: cutaneous leukocytoclastic angiitis
- Also called
- cutaneous hypersensitivity vasculitiscutaneous leukocytoclastic vasculitiscutaneous small vessel vasculitiscutaneous small-vessel vasculitishypersensitivity angiitis