CTNNA1-related diffuse gastric and lobular breast cancer syndrome
MONDO:0100256Mondo
Findings
No curated finding names CTNNA1-related diffuse gastric and lobular breast cancer syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Germline pathogenic or likely pathogenic variants in the CTNNA1 gene predispose to hereditary diffuse gastric cancer and lobular breast cancer, a cancer susceptibility syndrome inherited in an autosomal dominant pattern.
Definition from the Mondo Disease Ontology (MONDO:0100256), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- CTNNA1HGNC:2509
- Definitive · ClinGen · Autosomal dominant · 2023