cryopyrin-associated periodic syndrome
Findings
No curated finding names cryopyrin-associated periodic syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Cryopyrin associated periodic syndrome (CAPS) defines a group of autoinflammatory diseases, characterized by recurrent episodes of systemic inflammatory attacks in the absence of infection or autoimmune disease. CAPS comprises 3 disorders on a continuum of severity: severe CINCA syndrome, intermediate Muckle-Wells syndrome (MWS) and milder familial cold urticaria (FCAS).
Definition from the Mondo Disease Ontology (MONDO:0016168), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- NLRP3HGNC:16400
- Definitive · Illumina · Autosomal dominant · 2022
Where it sits
Other names
1 name
Resolves to: cryopyrin-associated periodic syndrome
- Also called
- Cryopyrinopathy