Cryoglobulinemic vasculitis
MONDO:0007407Mondo
Findings
No curated finding names Cryoglobulinemic vasculitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Mixed cryoglobulinemia (MC) is a rare multisystem disease characterized by the presence of circulating cryoprecipitable immune complexes in the serum, manifested clinically by a classical triad of purpura, weakness and arthralgia.
Definition from the Mondo Disease Ontology (MONDO:0007407), read 2026-09-29. CC BY 4.0.
Features
29 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Circulating immune complexesHPOHP:0012224
- Very frequent (80% to 99% of cases)
- CryoglobulinemiaHPOHP:0100778
- Very frequent (80% to 99% of cases)
- Cutis marmorataHPOHP:0000965
- Very frequent (80% to 99% of cases)
- FeverHPOHP:0001945
- Very frequent (80% to 99% of cases)
- Mediastinal lymphadenopathyHPOHP:0100721
- Very frequent (80% to 99% of cases)
- Muscle weaknessHPOHP:0001324
- Very frequent (80% to 99% of cases)
- PetechiaeHPOHP:0000967
- Very frequent (80% to 99% of cases)
- PurpuraHPOHP:0000979
- Very frequent (80% to 99% of cases)
- Skin ulcerHPOHP:0200042
- Very frequent (80% to 99% of cases)
- VasculitisHPOHP:0002633
- Very frequent (80% to 99% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- Abnormality of the liverHPOHP:0001392
- Frequent (30% to 79% of cases)
Show the remaining 17
- ArthralgiaHPOHP:0002829
- Frequent (30% to 79% of cases)
- ArthritisHPOHP:0001369
- Frequent (30% to 79% of cases)
- GangreneHPOHP:0100758
- Frequent (30% to 79% of cases)
- Gastrointestinal infarctionsHPOHP:0005244
- Frequent (30% to 79% of cases)
- GlomerulopathyHPOHP:0100820
- Frequent (30% to 79% of cases)
- HematuriaHPOHP:0000790
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
- Narrower terms (2)
Other names
5 names
Resolves to: Cryoglobulinemic vasculitis
- Also called
- essential cryoglobulinemiaessential mixed cryoglobulinemiaMCMixed Cryoglobulinemiaprimary cryoglobulinemia