criss-cross heart
Findings
No curated finding names criss-cross heart yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Criss cross heart (CCH) is a cardiac malformation where the inflow streams of the two ventricles cross due to twisting of the heart about its major axis. The clinical features depend on the particular cardiac defects associated, like simple or corrected transposition of the great arteries and ventricular septal defects.
Definition from the Mondo Disease Ontology (MONDO:0015449), read 2026-09-29. CC BY 4.0.
Features
13 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal cardiovascular system morphologyHPOHP:0030680
- Very frequent (80% to 99% of cases)
- CyanosisHPOHP:0000961
- Very frequent (80% to 99% of cases)
- Abnormal mitral valve morphologyHPOHP:0001633
- Frequent (30% to 79% of cases)
- Feeding difficultiesHPOHP:0011968
- Frequent (30% to 79% of cases)
- Mitral stenosisHPOHP:0001718
- Frequent (30% to 79% of cases)
- Pulmonic stenosisHPOHP:0001642
- Frequent (30% to 79% of cases)
- Respiratory insufficiencyHPOHP:0002093
- Frequent (30% to 79% of cases)
- Supravalvular aortic stenosisHPOHP:0004381
- Frequent (30% to 79% of cases)
- Transposition of the great arteriesHPOHP:0001669
- Frequent (30% to 79% of cases)
- Tricuspid stenosisHPOHP:0010446
- Frequent (30% to 79% of cases)
- Ventricular septal defectHPOHP:0001629
- Frequent (30% to 79% of cases)
- Abnormal facial shapeHPOHP:0001999
- Occasional (5% to 29% of cases)
Show the remaining 1
- Abnormal thorax morphologyHPOHP:0000765
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
3 names
Resolves to: criss-cross heart
- Also called
- criss-cross atrioventricular relationshipssuperoinferior ventriclestwisted atrioventricular connections