Crimean-Congo hemorrhagic fever
MONDO:0020501Mondo
Findings
No curated finding names Crimean-Congo hemorrhagic fever yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonotic disease caused by CCHF virus and characterized by initial fever, headache, and malaise followed by gastrointestinal symptoms and, in severe cases, bleeding, shock, and multi-organ system failure.
Definition from the Mondo Disease Ontology (MONDO:0020501), read 2026-09-29. CC BY 4.0.
Features
80 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Capillary leakHPOHP:0030005
- Very frequent (80% to 99% of cases)
- FeverHPOHP:0001945
- Very frequent (80% to 99% of cases)
- Increased circulating IgM concentrationHPOHP:0003496
- Very frequent (80% to 99% of cases)
- ThrombocytopeniaHPOHP:0001873
- Very frequent (80% to 99% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
- Decreased prothrombin timeHPOHP:0032198
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- Elevated circulating creatine kinase activityHPOHP:0003236
- Frequent (30% to 79% of cases)
- EpistaxisHPOHP:0000421
- Frequent (30% to 79% of cases)
- HeadacheHPOHP:0002315
- Frequent (30% to 79% of cases)
- HepatomegalyHPOHP:0002240
- Frequent (30% to 79% of cases)
Show the remaining 68
- Increased circulating IgG concentrationHPOHP:0003237
- Frequent (30% to 79% of cases)
- Increased circulating lactate dehydrogenase concentrationHPOHP:0025435
- Frequent (30% to 79% of cases)
- MyalgiaHPOHP:0003326
- Frequent (30% to 79% of cases)
- Nausea and vomitingHPOHP:0002017
- Frequent (30% to 79% of cases)
- Neck painHPOHP:0030833
- Frequent (30% to 79% of cases)
- Ocular painHPOHP:0200026
- Frequent (30% to 79% of cases)
Where it sits
Other names
7 names
Resolves to: Crimean-Congo hemorrhagic fever
- Also called
- CCHFCongo feverCongo hemorrhagic feverCongo-Crimean hemorrhagic feverCrimean hemorrhagic feverCrimean hemorrhagic fever [CHF Congo virus]Crimean-Congo haemorrhagic fever