craniopharyngioma
Findings
No curated finding names craniopharyngioma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A benign, partly cystic, epithelial tumor of the sellar region, presumably derived from Rathke pouch epithelium. It affects mainly children and young adults. There are two clinicopathological forms: adamantinomatous craniopharyngioma and papillary craniopharyngioma. The most significant factor associated with recurrence is the extent of surgical resection, with lesions greater than 5 cm in diameter carrying a markedly worse prognosis. (Adapted from WHO)
Definition from the Mondo Disease Ontology (MONDO:0018907), read 2026-09-29. CC BY 4.0.
Features
46 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal hypothalamus morphologyHPOHP:0012286
- Obligate (100% of cases)
- Cerebral calcificationHPOHP:0002514
- Very frequent (80% to 99% of cases)
- Enlarged pituitary glandHPOHP:0012505
- Very frequent (80% to 99% of cases)
- HypopituitarismHPOHP:0040075
- Very frequent (80% to 99% of cases)
- Intracranial cystic lesionHPOHP:0010576
- Very frequent (80% to 99% of cases)
- Neoplasm of the anterior pituitaryHPOHP:0011750
- Very frequent (80% to 99% of cases)
Show the remaining 34
- HypogonadismHPOHP:0000135
- Frequent (30% to 79% of cases)
- Hypogonadotropic hypogonadismHPOHP:0000044
- Frequent (30% to 79% of cases)
- Increased circulating prolactin concentrationHPOHP:0000870
- Frequent (30% to 79% of cases)
- Nausea and vomitingHPOHP:0002017
- Frequent (30% to 79% of cases)
- ObesityHPOHP:0001513
- Frequent (30% to 79% of cases)
- PapilledemaHPOHP:0001085
- Frequent (30% to 79% of cases)
Where it sits
Other names
12 names
Resolves to: craniopharyngioma
- Also called
- craniopharyngioma (morphologic abnormality)craniopharyngioma (WHO grade I)craniopharyngioma, benignneoplasm of Rathke's pouchRathke pouch neoplasmRathke pouch tumorRathke pouch tumourRathke's pouch neoplasmRathke's pouch tumorRathke's pouch tumourtumor of Rathke's pouchtumour of Rathke's pouch