corticobasal syndrome
MONDO:0018696Mondo
Findings
No curated finding names corticobasal syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Corticobasal syndrome (CBS) is a rare neurodegenerative disease characterized by multifaceted motor system dysfunctions and cognitive defects such as asymmetric rigidity, bradykinesia, limb apraxia, and visuospatial dysfunction.
Definition from the Mondo Disease Ontology (MONDO:0018696), read 2026-09-29. CC BY 4.0.
Features
23 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- MyoclonusHPOHP:0001336
- Very frequent (80% to 99% of cases)
- ParkinsonismHPOHP:0001300
- Very frequent (80% to 99% of cases)
- Progressive extrapyramidal muscular rigidityHPOHP:0007158
- Very frequent (80% to 99% of cases)
- AkinesiaHPOHP:0002304
- Frequent (30% to 79% of cases)
- BradykinesiaHPOHP:0002067
- Frequent (30% to 79% of cases)
- DementiaHPOHP:0000726
- Frequent (30% to 79% of cases)
- Frontal release signsHPOHP:0000743
- Frequent (30% to 79% of cases)
- Gait disturbanceHPOHP:0001288
- Frequent (30% to 79% of cases)
- Involuntary movementsHPOHP:0004305
- Frequent (30% to 79% of cases)
- Limb apraxiaHPOHP:0030217
- Frequent (30% to 79% of cases)
- Limb dystoniaHPOHP:0002451
- Frequent (30% to 79% of cases)
- Limb myoclonusHPOHP:0045084
- Frequent (30% to 79% of cases)
Show the remaining 11
- Oromotor apraxiaHPOHP:0007301
- Frequent (30% to 79% of cases)
- Postural instabilityHPOHP:0002172
- Frequent (30% to 79% of cases)
- Somatic sensory dysfunctionHPOHP:0003474
- Frequent (30% to 79% of cases)
- TremorHPOHP:0001337
- Frequent (30% to 79% of cases)
- AphasiaHPOHP:0002381
- Occasional (5% to 29% of cases)
- DystoniaHPOHP:0001332
- Occasional (5% to 29% of cases)