coronary artery disease, autosomal dominant, 1
Findings
No curated finding names coronary artery disease, autosomal dominant, 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene.
Definition from the Mondo Disease Ontology (MONDO:0012011), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Adult onset
HPO, annotations 2026-09-02
Features
7 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Premature coronary artery atherosclerosisHPOHP:0005181
- 13 of 13 reported patients
- HypercholesterolemiaHPOHP:0003124
- 9 of 13 reported patients
- Myocardial infarctionHPOHP:0001658
- 9 of 13 reported patients
- HypertensionHPOHP:0000822
- 8 of 13 reported patients
- Diabetes mellitusHPOHP:0000819
- 1 of 13 reported patients
- ObesityHPOHP:0001513
- 1 of 13 reported patients
- Chest painHPOHP:0100749
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- MEF2AHGNC:6993
- Limited · PanelApp Australia · Autosomal dominant · 2025
Where it sits
Other names
3 names
Resolves to: coronary artery disease, autosomal dominant, 1
- Also called
- coronary artery disease caused by mutation in MEF2Acoronary artery disease, autosomal dominant, type 1MEF2A coronary artery disease