corneal dystrophy, Fuchs endothelial, 6
Findings
No curated finding names corneal dystrophy, Fuchs endothelial, 6 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any Fuchs' endothelial dystrophy in which the cause of the disease is a mutation in the ZEB1 gene.
Definition from the Mondo Disease Ontology (MONDO:0013206), read 2026-09-29. CC BY 4.0.
Features
5 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal Descemet membrane morphologyHPOHP:0011490
- Corneal guttataHPOHP:0012038
- Corneal stromal edemaHPOHP:0012040
- KeratitisHPOHP:0000491
- Reduced visual acuityHPOHP:0007663
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- ZEB1HGNC:11642
- Strong · PanelApp Australia · Autosomal dominant · 2025
- Limited · G2P · Autosomal dominant · 2015
Where it sits
- A kind of
Other names
3 names
Resolves to: corneal dystrophy, Fuchs endothelial, 6
- Also called
- corneal dystrophy, Fuchs endothelial, type 6Fuchs' endothelial dystrophy caused by mutation in ZEB1ZEB1 Fuchs' endothelial dystrophy