congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization
Findings
No curated finding names congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A glomerular disease characterized by severe renal failure and nephrotic syndrome at birth, which rapidly improve in the first weeks of life.
Definition from the Mondo Disease Ontology (MONDO:0019068), read 2026-09-29. CC BY 4.0.
Features
4 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Glomerular depositsHPOHP:0030949
- Very frequent (80% to 99% of cases)
- GlomerulonephritisHPOHP:0000099
- Very frequent (80% to 99% of cases)
- Nephrotic syndromeHPOHP:0000100
- Very frequent (80% to 99% of cases)
- Renal insufficiencyHPOHP:0000083
- Frequent (30% to 79% of cases)
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- MMEHGNC:7154
- Supportive · Orphanet · Autosomal recessive · 2021
Where it sits
- A kind of
Other names
6 names
Resolves to: congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization
- Also called
- alloimmune neonatal renal diseasefetomaternal alloimmunization with antenatal glomerulopathiesFMAIGneonatal glomerulopathy due to Neprilysin alloimmunizationneonatal membranous glomerulopathy with maternal NEP deficiencyneonatal membranous glomerulopathy with maternal neutral endopeptidase deficiency