congenital lobar emphysema
MONDO:0007536Mondo
Findings
No curated finding names congenital lobar emphysema yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Congenital lobar emphysema (CLE) is a respiratory abnormality characterized by respiratory distress due to hyperinflation of one or more affected lobes of the lung.
Definition from the Mondo Disease Ontology (MONDO:0007536), read 2026-09-29. CC BY 4.0.
Features
13 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- EmphysemaHPOHP:0002097
- Very frequent (80% to 99% of cases)
- Respiratory distressHPOHP:0002098
- Very frequent (80% to 99% of cases)
- Abnormality of immune system physiologyHPOHP:0010978
- Frequent (30% to 79% of cases)
- CyanosisHPOHP:0000961
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- Mediastinal shiftHPOHP:6000012
- Frequent (30% to 79% of cases)
- TachycardiaHPOHP:0001649
- Frequent (30% to 79% of cases)
- WheezingHPOHP:0030828
- Frequent (30% to 79% of cases)
- Abnormal cardiovascular system morphologyHPOHP:0030680
- Occasional (5% to 29% of cases)
- Asymmetry of the thoraxHPOHP:0001555
- Occasional (5% to 29% of cases)
- AtelectasisHPOHP:0100750
- Occasional (5% to 29% of cases)
- Failure to thriveHPOHP:0001508
- Occasional (5% to 29% of cases)
Show the remaining 1
- Feeding difficultiesHPOHP:0011968
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: congenital lobar emphysema
- Also called
- CLEcongenital lobar hyperinflationEmphysema, Congenital Lobarinfantile lobar hyperinflation