complex regional pain syndrome
Findings
No curated finding names complex regional pain syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A chronic pain syndrome characterized by a disproportionate spontaneous or stimulus-induced pain, accompanied by a variably mixed myriad of autonomic and motor disorders including symptoms such as swelling, allodynia, skin blood supply and trophic disturbances. CRPS most often affects one of the arms, legs, hands, or feet and usually occurs after an injury or trauma to that limb.
Definition from the Mondo Disease Ontology (MONDO:0019369), read 2026-09-29. CC BY 4.0.
Features
12 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Limb painHPOHP:0009763
- Very frequent (80% to 99% of cases)
- Abnormality of hair growthHPOHP:0040170
- Frequent (30% to 79% of cases)
- AllodyniaHPOHP:0012533
- Frequent (30% to 79% of cases)
- Dry skinHPOHP:0000958
- Frequent (30% to 79% of cases)
- DysesthesiaHPOHP:0012534
- Frequent (30% to 79% of cases)
- Edema of the upper limbsHPOHP:0010742
- Frequent (30% to 79% of cases)
- ErythemaHPO
Where it sits
- A kind of
Other names
2 names
Resolves to: complex regional pain syndrome
- Also called
- algoneurodystrophyCRPS