colchicine poisoning
Findings
No curated finding names colchicine poisoning yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A potentially life-threatening poisoning, due to ingestion of the drug or consumption of the plant Colchicum autumnale, that usually begins with gastrointestinal symptoms (e.g. abdominal pain, nausea, vomiting, and diarrhea, that cause severe dehydration) and an initial leukocytosis leading to marrow failure (24 hours after ingestion), followed by potentially fatal multi-organ failure with mental status change, oliguric renal failure, disseminated intravascular coagulation, electrolyte imbalance, acid-base disturbance, cardiac failure/arrest and shock within 1-3 days.
Definition from the Mondo Disease Ontology (MONDO:0017859), read 2026-09-29. CC BY 4.0.
Features
29 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- DehydrationHPOHP:0001944
- Very frequent (80% to 99% of cases)
- HypotensionHPOHP:0002615
- Very frequent (80% to 99% of cases)
- Increased total leukocyte countHPOHP:0001974
- Very frequent (80% to 99% of cases)
- Metabolic acidosisHPOHP:0001942
- Very frequent (80% to 99% of cases)
- NauseaHPOHP:0002018
- Very frequent (80% to 99% of cases)
- Respiratory distressHPOHP:0002098
- Very frequent (80% to 99% of cases)
- Vomiting
Show the remaining 17
- Cardiogenic shockHPOHP:0030149
- Frequent (30% to 79% of cases)
- Cardiorespiratory arrestHPOHP:0006543
- Frequent (30% to 79% of cases)
- Congestive heart failureHPOHP:0001635
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- Disseminated intravascular coagulationHPOHP:0005521
- Frequent (30% to 79% of cases)
- HypocalcemiaHPOHP:0002901
- Frequent (30% to 79% of cases)
Where it sits
- A kind of