cocaine embryofetopathy
Findings
No curated finding names cocaine embryofetopathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A group of clinical signs observed in newborns exposed in utero to cocaine, a short-acting central nervous system stimulant used as a recreational drug through inhalation of the powder or intravenous injection. Cocaine use during pregnancy is associated with intrauterine growth restriction, low birth weight, seizures, respiratory distress (decreased apnea density and periodic breathing), feeding difficulties, irritability and lability of state, decreased behavioral and autonomic regulation, poor alertness and orientation and cognitive impairment (impaired auditory information processing, visual-spatial delay and subtle language delay) in the offspring.
Definition from the Mondo Disease Ontology (MONDO:0016007), read 2026-09-29. CC BY 4.0.
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- HyperreflexiaHPOHP:0001347
- Very frequent (80% to 99% of cases)
- HypertoniaHPOHP:0001276
- Very frequent (80% to 99% of cases)
- Abnormality of the cardiovascular systemHPOHP:0001626
- Occasional (5% to 29% of cases)
- Abnormality of the urinary systemHPOHP:0000079
- Occasional (5% to 29% of cases)
- EncephaloceleHPOHP:0002084
- Occasional (5% to 29% of cases)
- Intestinal atresiaHPOHP:0011100
- Occasional (5% to 29% of cases)
- Short distal phalanx of finger
Where it sits
Other names
2 names
Resolves to: cocaine embryofetopathy
- Also called
- fetal cocaine syndromefoetal cocaine syndrome