Coats disease
Findings
No curated finding names Coats disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Coats disease (CD) is an idiopathic disorder characterized by retinal telangiectasia with deposition of intraretinal or subretinal exudates, potentially leading to retinal detachment and unilateral blindness. CD is classically an isolated and unilateral condition affecting otherwise healthy young children.
Definition from the Mondo Disease Ontology (MONDO:0010269), read 2026-09-29. CC BY 4.0.
- Inheritance
- Typified by somatic mosaicism
HPO, annotations 2026-09-02
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal retinal vascular morphologyHPOHP:0008046
- Very frequent (80% to 99% of cases)
- StrabismusHPOHP:0000486
- Very frequent (80% to 99% of cases)
- Abnormal macular morphologyHPOHP:0001103
- Frequent (30% to 79% of cases)
- GlaucomaHPOHP:0000501
- Frequent (30% to 79% of cases)
- Retinal detachmentHPOHP:0000541
- Frequent (30% to 79% of cases)
- Abnormal anterior chamber morphologyHPOHP:0000593
- Occasional (5% to 29% of cases)
- Aplasia/Hypoplasia of the iris
Where it sits
Other names
3 names
Resolves to: Coats disease
- Also called
- congenital retinal telangiectasiaexudative retinopathyLeber miliary aneurysm