classic paraneoplastic limbic encephalitis
Findings
No curated finding names classic paraneoplastic limbic encephalitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Classic paraneoplastic limbic encephalitis is a rare neuroimmunological disorder characterized by the sudden onset of seizures, progressive memory impairment (which may develop into dementia) and psychiatric manifestations (e.g. depression, personality changes, loss of social inhibition) associated with cancer (most commonly small-cell carcinoma of the lung) in the absence of tumor cell invasion of the nervous system. Other reported features include ataxia, dystonia, paresthesia, tremors, paranoid ideation, and hallucinations. The presence of antibodies that act on neuronal antigens (such as anti-Hu, anti-Ma2, anti-amphiphysin) are typically observed.
Definition from the Mondo Disease Ontology (MONDO:0015590), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
1 name
Resolves to: classic paraneoplastic limbic encephalitis
- Also called
- classic paraneoplastic limbic encephalitis, with or without intracellular antigens