chronic inflammatory demyelinating polyradiculoneuropathy
Findings
No curated finding names chronic inflammatory demyelinating polyradiculoneuropathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare neurological disorder in which there is inflammation of nerve roots and peripheral nerves and destruction of the fatty protective covering (myelin sheath) over the nerves. This affects how fast the nerve signals are transmitted and leads to loss of nerve fibers. This causes weakness, paralysis and/or impairment in motor function, especially of the arms and legs (limbs). Sensory disturbance may also be present. The motor and sensory impairments usually affect both sides of the body (symmetrical), and the degree of severity and the course of disease may vary from case to case. Some affected individuals may follow a slow steady pattern of symptoms while others may have symptoms that stabilize and then relapse.
Definition from the Mondo Disease Ontology (MONDO:0006702), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal nerve conduction velocityHPOHP:0040129
- Very frequent (80% to 99% of cases)
- AreflexiaHPOHP:0001284
- Very frequent (80% to 99% of cases)
- Decreased nerve conduction velocityHPOHP:0000762
- Very frequent (80% to 99% of cases)
- Fatiguable weakness of proximal limb musclesHPOHP:0030200
- Very frequent (80% to 99% of cases)
- Motor conduction blockHPOHP:0012078
- Very frequent (80% to 99% of cases)
- ParesthesiaHPOHP:0003401
- Very frequent (80% to 99% of cases)
Show the remaining 5
- Difficulty climbing stairsHPOHP:0003551
- Frequent (30% to 79% of cases)
- FallsHPOHP:0002527
- Frequent (30% to 79% of cases)
- Gait disturbanceHPOHP:0001288
- Frequent (30% to 79% of cases)
- Hand muscle weaknessHPOHP:0030237
- Frequent (30% to 79% of cases)
- Spontaneous pain sensationHPOHP:0010833
- Occasional (5% to 29% of cases)
Where it sits
Other names
3 names
Resolves to: chronic inflammatory demyelinating polyradiculoneuropathy
- Also called
- chronic inflammatory demyelinating polyneuropathychronic relapsing polyneuropathyCIDP