chromosome 15q24 deletion syndrome
Findings
No curated finding names chromosome 15q24 deletion syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
15q24 microdeletion syndrome is a rare chromosomal anomaly characterized cytogenetically by a 1.7-6.1 Mb deletion in chromosome 15q24 and clinically by pre- and post-natal growth retardation, intellectual disability, distinct facial features, and genital, skeletal, and digital anomalies.
Definition from the Mondo Disease Ontology (MONDO:0013256), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance · Sporadic
- Onset and course
- Congenital onset · Infantile onset · Neonatal onset · Childhood onset · Second trimester onset
HPO, annotations 2026-09-02
Features
131 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Aggressive behaviorHPOHP:0000718
- 1 of 1 reported patient
- Congenital diaphragmatic herniaHPOHP:0000776
- 1 of 1 reported patient
- Occasional (5% to 29% of cases)
- HyperactivityHPOHP:0000752
- 1 of 1 reported patient
- HypertelorismHPOHP:0000316
- 1 of 1 reported patient
- Occasional (5% to 29% of cases)
- IncoordinationHPOHP:0002311
- 1 of 1 reported patient
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SIN3AHGNC:19353
- Strong · Ambry Genetics · Autosomal dominant · 2018
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
- Strong · PanelApp Australia · Autosomal dominant · 2025
Where it sits
Other names
4 names
Resolves to: chromosome 15q24 deletion syndrome
- Also called
- 15q24 microdeletion syndrome15q24 recurrent microdeletion syndromeDel(15)(q24)monosomy 15q24