chordoma
MONDO:0008978Mondo
Findings
No curated finding names chordoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Chordomas are rare malignant tumors arising from embryonic remnants of the notochord in axial skeleton.
Definition from the Mondo Disease Ontology (MONDO:0008978), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset · Juvenile onset · Young adult onset
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- ChordomaHPOHP:0010762
- 15 of 16 reported patients
- AstrocytomaHPOHP:0009592
- 1 of 16 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TBXTHGNC:11515
- Strong · Genomics England PanelApp · Autosomal dominant · 2021
Where it sits
- A kind of
Other names
3 names
Resolves to: chordoma
- Also called
- chordoma (disease)chordoma, malignantnotochordal sarcoma