cholangiocarcinoma
Findings
No curated finding names cholangiocarcinoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A carcinoma that arises from the intrahepatic biliary tree (intrahepatic cholangiocarcinoma) or from the junction, or adjacent to the junction, of the right and left hepatic ducts (hilar cholangiocarcinoma). Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.
Definition from the Mondo Disease Ontology (MONDO:0019087), read 2026-09-29. CC BY 4.0.
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Acholic stoolsHPOHP:0011985
- Very frequent (80% to 99% of cases)
- Biliary tract neoplasmHPOHP:0100574
- Very frequent (80% to 99% of cases)
- JaundiceHPOHP:0000952
- Very frequent (80% to 99% of cases)
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
- PruritusHPOHP:0000989
- Frequent (30% to 79% of cases)
- Abdominal painHPOHP:0002027
- Occasional (5% to 29% of cases)
- AnorexiaHPO
Where it sits
- Narrower terms (1)
Other names
6 names
Resolves to: cholangiocarcinoma
- Also called
- CCCCACholangiocar.- intra/extrahepaticcholangiocarcinoma, intrahepatic and extrahepatic bile ducts (adenocarcinoma)cholangiocarcinoma, malignantCholangiocellular carcinoma