central diabetes insipidus
MONDO:0015790Mondo
Findings
No curated finding names central diabetes insipidus yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Central diabetes insipidus (CDI) is a hypothalamus-pituitary disease characterized by polyuria and polydipsia due to a vasopressin (AVP) deficiency. It can be inherited or acquired (hereditary CDI and acquired CDI).
Definition from the Mondo Disease Ontology (MONDO:0015790), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AnorexiaHPOHP:0002039
- Very frequent (80% to 99% of cases)
- DehydrationHPOHP:0001944
- Very frequent (80% to 99% of cases)
- Diabetes insipidusHPOHP:0000873
- Very frequent (80% to 99% of cases)
- Failure to thriveHPOHP:0001508
- Very frequent (80% to 99% of cases)
- NocturiaHPOHP:0000017
- Very frequent (80% to 99% of cases)
- PolydipsiaHPOHP:0001959
- Very frequent (80% to 99% of cases)
- Weight lossHPOHP:0001824
- Very frequent (80% to 99% of cases)
- AnxietyHPOHP:0000739
- Frequent (30% to 79% of cases)
- DepressionHPOHP:0000716
- Frequent (30% to 79% of cases)
- Excessive daytime somnolenceHPOHP:0001262
- Frequent (30% to 79% of cases)
- FeverHPOHP:0001945
- Frequent (30% to 79% of cases)
- HeadacheHPOHP:0002315
- Frequent (30% to 79% of cases)
Show the remaining 5
- LethargyHPOHP:0001254
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Occasional (5% to 29% of cases)
- HyponatremiaHPOHP:0002902
- Occasional (5% to 29% of cases)
- Nausea and vomitingHPOHP:0002017
- Occasional (5% to 29% of cases)
- SeizureHPOHP:0001250
- Occasional (5% to 29% of cases)
Where it sits
- Narrower terms (2)
Other names
2 names
Resolves to: central diabetes insipidus
- Also called
- CDIneurogenic diabetes insipidus