caudal regression sequence
MONDO:0017607Mondo
Findings
No curated finding names caudal regression sequence yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Caudal regression sequence is a rare congenital malformation of the lower spinal segments associated with aplasia or hypoplasia of the sacrum and lumbar spine.
Definition from the Mondo Disease Ontology (MONDO:0017607), read 2026-09-29. CC BY 4.0.
Features
28 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal iliac wing morphologyHPOHP:0011867
- Very frequent (80% to 99% of cases)
- Abnormal pelvic girdle bone morphologyHPOHP:0002644
- Very frequent (80% to 99% of cases)
- Abnormal vertebral segmentation and fusionHPOHP:0005640
- Very frequent (80% to 99% of cases)
- Aplasia/Hypoplasia of the sacrumHPOHP:0008517
- Very frequent (80% to 99% of cases)
- Bowel incontinenceHPOHP:0002607
- Very frequent (80% to 99% of cases)
- Decreased muscle massHPOHP:0003199
- Very frequent (80% to 99% of cases)
- Hypoplastic vertebral bodiesHPOHP:0008479
- Very frequent (80% to 99% of cases)
- ImpulsivityHPOHP:0100710
- Very frequent (80% to 99% of cases)
- Abnormal cardiovascular system morphologyHPOHP:0030680
- Frequent (30% to 79% of cases)
- Abnormality of the ureterHPOHP:0000069
- Frequent (30% to 79% of cases)
- Anal atresiaHPOHP:0002023
- Frequent (30% to 79% of cases)
- Diminished deep tendon reflexHPOHP:0001315
- Frequent (30% to 79% of cases)
Show the remaining 16
- Ectopic kidneyHPOHP:0000086
- Frequent (30% to 79% of cases)
- Joint stiffnessHPOHP:0001387
- Frequent (30% to 79% of cases)
- Renal agenesisHPOHP:0000104
- Frequent (30% to 79% of cases)
- ScoliosisHPOHP:0002650
- Frequent (30% to 79% of cases)
- Talipes equinovarusHPOHP:0001762
- Frequent (30% to 79% of cases)
- Ureteral duplicationHPOHP:0000073
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: caudal regression sequence
- Also called
- caudal dysplasiaCaudal Regression Syndromesacral agenesis syndromesacral regression syndrome