cardiomyopathy, familial hypertrophic, 28
MONDO:0030317Mondo
Findings
No curated finding names cardiomyopathy, familial hypertrophic, 28 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Adult onset
HPO, annotations 2026-09-02
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Asymmetric septal hypertrophyHPOHP:0001670
- 35 of 41 reported patients
- Myocardial late gadolinium enhancementHPOHP:4000004
- 11 of 17 reported patients
- Left atrial enlargementHPOHP:0031295
- 19 of 39 reported patients
- Left ventricular outflow tract obstructionHPOHP:0032092
- 9 of 42 reported patients
- Sudden cardiac deathHPOHP:0001645
- 11 of 68 reported patients
- Reduced left ventricular ejection fractionHPOHP:0012664
- 6 of 46 reported patients
- Systolic anterior motion of the mitral valveHPOHP:0031656
- 5 of 40 reported patients
- Atrial fibrillationHPOHP:0005110
- 6 of 55 reported patients
- Concentric hypertrophic cardiomyopathyHPOHP:0005157
- 4 of 41 reported patients
- StrokeHPOHP:0001297
- 5 of 64 reported patients
- Apical hypertrophic cardiomyopathyHPOHP:0031992
- 2 of 41 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- FHOD3HGNC:26178
- Strong · Ambry Genetics · Autosomal dominant · 2023
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2022
- Strong · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
1 name
Resolves to: cardiomyopathy, familial hypertrophic, 28
- Also called
- CMH28