cardiac conduction disease with or without dilated cardiomyopathy 1
Findings
No curated finding names cardiac conduction disease with or without dilated cardiomyopathy 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A hereditary atrial tachyarrhythmia-infra-Hisian cardiac conduction disease caused by a variation in the TNNI3K gene.
Definition from the Mondo Disease Ontology (MONDO:0700388), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
3 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Atrial arrhythmiaHPOHP:0001692
- Dilated cardiomyopathyHPOHP:0001644
- Left anterior fascicular blockHPOHP:0011711
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TNNI3KHGNC:19661
- Strong · PanelApp Australia · Autosomal dominant · 2025