cardiac conduction disease with or without cardiomyopathy 2
MONDO:0700389Mondo
Findings
No curated finding names cardiac conduction disease with or without cardiomyopathy 2 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A hereditary atrial tachyarrhythmia-infra-Hisian cardiac conduction disease caused by a variation in the POPDC2 gene.
Definition from the Mondo Disease Ontology (MONDO:0700389), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Juvenile onset · Young adult onset
HPO, annotations 2026-09-02
Features
21 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Chest painHPOHP:0100749
- 1 of 1 reported patient
- First degree atrioventricular blockHPOHP:0011705
- 6 of 6 reported patients
- Mobitz I atrioventricular blockHPOHP:0011707
- 2 of 2 reported patients
- PalpitationsHPOHP:0001962
- 2 of 2 reported patients
- Monomorphic ventricular tachycardiaHPOHP:0031676
- 3 of 4 reported patients
- Myocardial fibrosisHPOHP:0001685
- 2 of 3 reported patients
- 2:1 atrioventricular blockHPO
Show the remaining 9
- Fatty replacement of ventricular myocardial tissueHPOHP:0031317
- 1 of 3 reported patients
- Hypertrophic cardiomyopathyHPOHP:0001639
- 2 of 6 reported patients
- MyocarditisHPOHP:0012819
- 2 of 6 reported patients
- Second degree atrioventricular blockHPOHP:0011706
- 1 of 3 reported patients
- Sinus bradycardiaHPOHP:0001688
- 1 of 3 reported patients
- Ventricular tachycardiaHPOHP:0004756
- 1 of 3 reported patients