capillary leak syndrome
Findings
No curated finding names capillary leak syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A syndrome characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure.
Definition from the Mondo Disease Ontology (MONDO:0001956), read 2026-09-29. CC BY 4.0.
Features
23 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Increased total leukocyte countHPOHP:0001974
- Very frequent (80% to 99% of cases)
- Pedal edemaHPOHP:0010741
- Very frequent (80% to 99% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- Constitutional symptomHPOHP:0025142
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
- HypotensionHPO
Show the remaining 11
- Abnormal renal tubule morphologyHPOHP:0000091
- Occasional (5% to 29% of cases)
- ArrhythmiaHPOHP:0011675
- Occasional (5% to 29% of cases)
- Cardiorespiratory arrestHPOHP:0006543
- Occasional (5% to 29% of cases)
- CoughHPOHP:0012735
- Occasional (5% to 29% of cases)
- Multiple myelomaHPOHP:0006775
- Occasional (5% to 29% of cases)
- MyocarditisHPOHP:0012819
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
8 names
Resolves to: capillary leak syndrome
- Also called
- acute vascular leak syndromeAVLScapillary hyperpermeability syndromeClarkson diseaseCLSidiopathic capillary leak syndromeSCLSSystemic Capillary Leak Syndrome