candidiasis, familial, 8
Findings
No curated finding names candidiasis, familial, 8 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any chronic mucocutaneous candidiasis in which the cause of the disease is a mutation in the TRAF3IP2 gene.
Definition from the Mondo Disease Ontology (MONDO:0014230), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Juvenile onset · Childhood onset
HPO, annotations 2026-09-02
Features
6 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Recurrent oral thrushHPOHP:0009098
- 2 of 2 reported patients
- Seborrheic dermatitisHPOHP:0001051
- 2 of 2 reported patients
- BlepharitisHPOHP:0000498
- 1 of 2 reported patients
- CheilitisHPOHP:0100825
- 1 of 2 reported patients
- MacroglossiaHPOHP:0000158
- 1 of 2 reported patients
- Unusual fungal nail infectionHPOHP:0012203
- 1 of 2 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TRAF3IP2HGNC:1343
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2022
- Moderate · PanelApp Australia · Autosomal recessive · 2025
- Moderate · LiferaOmics · Autosomal recessive · 2026
Where it sits
- A kind of
Other names
3 names
Resolves to: candidiasis, familial, 8
- Also called
- candidiasis, familial, type 8chronic mucocutaneous candidiasis (disease) caused by mutation in TRAF3IP2TRAF3IP2 chronic mucocutaneous candidiasis (disease)