cancer-associated retinopathy
MONDO:0019112Mondo
Findings
No curated finding names cancer-associated retinopathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Cancer associated retinopathy (CAR) is a paraneoplastic disease of the eye associated with the presence of extraocular malignancy and circulating autoantibodies against retinal proteins.
Definition from the Mondo Disease Ontology (MONDO:0019112), read 2026-09-29. CC BY 4.0.
Features
36 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Adult-onset night blindnessHPOHP:0007830
- Frequent (30% to 79% of cases)
- Anti-recoverin antibody positivityHPOHP:6000882
- Frequent (30% to 79% of cases)
- Autoimmune antibody positivityHPOHP:0030057
- Frequent (30% to 79% of cases)
- ERG: Reduced dark-adapted b-wave amplitudeHPOHP:0007984
- Frequent (30% to 79% of cases)
- Female reproductive system neoplasmHPOHP:0033020
- Frequent (30% to 79% of cases)
- Malignant genitourinary tract tumorHPOHP:0006758
- Frequent (30% to 79% of cases)
- Neoplasm of the breastHPOHP:0100013
- Frequent (30% to 79% of cases)
- PhotophobiaHPOHP:0000613
- Frequent (30% to 79% of cases)
- PhotopsiaHPOHP:0030786
- Frequent (30% to 79% of cases)
- Progressive visual field defectsHPOHP:0007987
- Frequent (30% to 79% of cases)
- Reduced visual acuityHPOHP:0007663
- Frequent (30% to 79% of cases)
- Small cell lung carcinomaHPOHP:0030357
- Frequent (30% to 79% of cases)
Show the remaining 24
- Visual lossHPOHP:0000572
- Frequent (30% to 79% of cases)
- Central scotomaHPOHP:0000603
- Occasional (5% to 29% of cases)
- Constriction of peripheral visual fieldHPOHP:0001133
- Occasional (5% to 29% of cases)
- Diffuse cerebellar atrophyHPOHP:0100275
- Occasional (5% to 29% of cases)
- DyschromatopsiaHPOHP:0007641
- Occasional (5% to 29% of cases)
- Foveal hyporeflective spaces on macular OCTHPOHP:0030627
- Occasional (5% to 29% of cases)
Where it sits
Other names
2 names
Resolves to: cancer-associated retinopathy
- Also called
- CAR syndromeparaneoplastic retinopathy