Brugada syndrome 6
MONDO:0013145Mondo
Findings
No curated finding names Brugada syndrome 6 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any Brugada syndrome in which the cause of the disease is a mutation in the KCNE3 gene.
Definition from the Mondo Disease Ontology (MONDO:0013145), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
3 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- ST segment elevationHPOHP:0012251
- 4 of 4 reported patients
- Cardiac arrestHPOHP:0001695
- Ventricular fibrillationHPOHP:0001663
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- KCNE3HGNC:6243
- Limited · Genomics England PanelApp · Unknown · 2021
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2020
- Disputed Evidence · Laboratory for Molecular Medicine · Unknown · 2020
- Disputed Evidence · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
4 names
Resolves to: Brugada syndrome 6
- Also called
- BRGDA6Brugada syndrome caused by mutation in KCNE3Brugada syndrome type 6KCNE3 Brugada syndrome