brucellosis

MONDO:0005683Mondo

Findings

No curated finding names brucellosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Brucellosis is a bacterial infection that spreads from animals to people via unpasteurized dairy products or by exposure to contaminated animal products or infected animals. Animals that are most commonly infected include sheep, cattle, goats, pigs, and dogs. Brucellosis can cause of range of signs and symptoms, some of which may persist or recur. Initial symptoms may include fever, sweats, malaise, anorexia, headache, fatigue, and/or pain in the muscles, joints, and/or back. Symptoms that may persist or recur include fevers, arthritis, swelling of the testicle and scrotum, swelling of the heart (endocarditis), neurologic symptoms (in up to 5% of cases), chronic fatigue, depression, and/or swelling of the liver or spleen. People who are in jobs or settings that increase exposure to the bacteria are at increased risk for infection. Antibiotics are used to treat brucellosis. Recovery may take a few weeks to several months, and relapses are common. Death from brucellosis is rare, occurring in no more than 2% of cases.

Definition from the Mondo Disease Ontology (MONDO:0005683), read 2026-09-29. CC BY 4.0.

Onset and course: Miscarriage

Features

76 features

What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.

Abnormality of the liverHPOHP:0001392
- Very frequent (80% to 99% of cases)
Abnormal hepatobiliary system physiologyHPOHP:0025155
- Frequent (30% to 79% of cases)
Abnormality of the gastrointestinal tractHPOHP:0011024
- Frequent (30% to 79% of cases)
AnemiaHPOHP:0001903
- Frequent (30% to 79% of cases)
AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
Arthralgia

Where it sits

A kind of: primary bacterial infectious disease
Narrower terms (4): Brucella abortus brucellosis
Brucella canis brucellosis
Brucella melitensis brucellosis
Brucella suis brucellosis

Other names

1 name

Resolves to: brucellosis

Also called: undulant fever

Show the remaining 64

FeverHPOHP:0001945
- Frequent (30% to 79% of cases)
HepatomegalyHPOHP:0002240
- Frequent (30% to 79% of cases)
HyperhidrosisHPOHP:0000975
- Frequent (30% to 79% of cases)
Increased circulating IgG concentrationHPOHP:0003237
- Frequent (30% to 79% of cases)
NauseaHPOHP:0002018
- Frequent (30% to 79% of cases)
Septic arthritisHPOHP:0003095
- Frequent (30% to 79% of cases)
SplenomegalyHPOHP:0001744
- Frequent (30% to 79% of cases)
Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
Abdominal painHPOHP:0002027
- Occasional (5% to 29% of cases)
Abnormal bone marrow cell morphologyHPOHP:0005561
- Occasional (5% to 29% of cases)
Abnormal respiratory system morphologyHPOHP:0012252
- Occasional (5% to 29% of cases)
Abnormality of the genitourinary systemHPOHP:0000119
- Occasional (5% to 29% of cases)
Abnormality of the nervous systemHPOHP:0000707
- Occasional (5% to 29% of cases)
Abnormality of the peripheral nervous systemHPOHP:0410008
- Occasional (5% to 29% of cases)
Abnormality of the skinHPOHP:0000951
- Occasional (5% to 29% of cases)
BronchitisHPOHP:0012387
- Occasional (5% to 29% of cases)
ChillsHPOHP:0025143
- Occasional (5% to 29% of cases)
Cutaneous cystHPOHP:0025245
- Occasional (5% to 29% of cases)
DepressionHPOHP:0000716
- Occasional (5% to 29% of cases)
EpididymitisHPOHP:0000031
- Occasional (5% to 29% of cases)
Erythematous papuleHPOHP:0030350
- Occasional (5% to 29% of cases)
Failure to thriveHPOHP:0001508
- Occasional (5% to 29% of cases)
GlomerulonephritisHPOHP:0000099
- Occasional (5% to 29% of cases)
GranulomaHPOHP:0032252
- Occasional (5% to 29% of cases)
HeadacheHPOHP:0002315
- Occasional (5% to 29% of cases)
Hip osteoarthritisHPOHP:0008843
- Occasional (5% to 29% of cases)
HypersplenismHPOHP:0001971
- Occasional (5% to 29% of cases)
Immunologic hypersensitivityHPOHP:0100326
- Occasional (5% to 29% of cases)
Increased circulating IgM concentrationHPOHP:0003496
- Occasional (5% to 29% of cases)
Increased total leukocyte countHPOHP:0001974
- Occasional (5% to 29% of cases)
Knee osteoarthritisHPOHP:0005086
- Occasional (5% to 29% of cases)
Liver abscessHPOHP:0100523
- Occasional (5% to 29% of cases)
LymphadenopathyHPOHP:0002716
- Occasional (5% to 29% of cases)
Morphological central nervous system abnormalityHPOHP:0002011
- Occasional (5% to 29% of cases)
OrchitisHPOHP:0100796
- Occasional (5% to 29% of cases)
OsteomyelitisHPOHP:0002754
- Occasional (5% to 29% of cases)
Peripheral neuropathyHPOHP:0009830
- Occasional (5% to 29% of cases)
Pleural effusionHPOHP:0002202
- Occasional (5% to 29% of cases)
PneumoniaHPOHP:0002090
- Occasional (5% to 29% of cases)
Premature birthHPOHP:0001622
- Occasional (5% to 29% of cases)
PurpuraHPOHP:0000979
- Occasional (5% to 29% of cases)
Rheumatoid factor positiveHPOHP:0002923
- Occasional (5% to 29% of cases)
Sacroiliac arthritisHPOHP:0012317
- Occasional (5% to 29% of cases)
Small for gestational ageHPOHP:0001518
- Occasional (5% to 29% of cases)
ThrombocytopeniaHPOHP:0001873
- Occasional (5% to 29% of cases)
VomitingHPOHP:0002013
- Occasional (5% to 29% of cases)
Abnormal aortic valve morphologyHPOHP:0001646
- Very rare (1% to 4% of cases)
Abnormal cranial nerve physiologyHPOHP:0031910
- Very rare (1% to 4% of cases)
Abnormality of the cardiovascular systemHPOHP:0001626
- Very rare (1% to 4% of cases)
Anterior uveitisHPOHP:0012122
- Very rare (1% to 4% of cases)
ArteritisHPOHP:0012089
- Very rare (1% to 4% of cases)
Atypical behaviorHPOHP:0000708
- Very rare (1% to 4% of cases)
ChoreaHPOHP:0002072
- Very rare (1% to 4% of cases)
ChorioretinitisHPOHP:0012424
- Very rare (1% to 4% of cases)
EndocarditisHPOHP:0100584
- Very rare (1% to 4% of cases)
Infectious encephalitisHPOHP:0002383
- Very rare (1% to 4% of cases)
Intrarenal abscessHPOHP:0032620
- Very rare (1% to 4% of cases)
Lung abscessHPOHP:0025044
- Very rare (1% to 4% of cases)
MyocarditisHPOHP:0012819
- Very rare (1% to 4% of cases)
PericarditisHPOHP:0001701
- Very rare (1% to 4% of cases)
Pulmonary granulomatosisHPOHP:0030250
- Very rare (1% to 4% of cases)
ThrombocytosisHPOHP:0001894
- Very rare (1% to 4% of cases)
ThrombophlebitisHPOHP:0004418
- Very rare (1% to 4% of cases)
Transient ischemic attackHPOHP:0002326
- Very rare (1% to 4% of cases)