breast-ovarian cancer, familial, susceptibility to, 3
Findings
No curated finding names breast-ovarian cancer, familial, susceptibility to, 3 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any hereditary breast ovarian cancer syndrome in which the cause of the disease is a mutation in the RAD51C gene.
Definition from the Mondo Disease Ontology (MONDO:0013253), read 2026-09-29. CC BY 4.0.
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Breast carcinomaHPOHP:0003002
- Middle age onset · Female
- Ovarian carcinomaHPOHP:0025318
- Middle age onset · Female
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- RAD51CHGNC:9820
- Strong · Genomics England PanelApp · Autosomal dominant · 2020
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
- Limited · Ambry Genetics · Autosomal dominant · 2022
Where it sits
Other names
3 names
Resolves to: breast-ovarian cancer, familial, susceptibility to, 3
- Also called
- breast-ovarian cancer, familial, susceptibility to, type 3hereditary breast ovarian cancer syndrome caused by mutation in RAD51CRAD51C hereditary breast ovarian cancer syndrome