BN2 diffuse large B-cell lymphoma
MONDO:0850468Mondo
Findings
No curated finding names BN2 diffuse large B-cell lymphoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A diffuse large B-cell lymphoma that is categorized as BN2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and BN2 DLBCLs often, but do not always, have a translocation involving the BCL6 locus and/or some combination of mutations affecting NOTCH2, TNFAIP3, BCL10 and UBE2A. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting CD70, which can be coding or non-coding.
Definition from the Mondo Disease Ontology (MONDO:0850468), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of