blue rubber bleb nevus
MONDO:0007203Mondo
Findings
No curated finding names blue rubber bleb nevus yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Blue rubber bleb nevus (BRBNS) is a rare vascular malformation disorder with cutaneous and visceral lesions frequently associated with serious, potentially fatal bleeding and anemia.
Definition from the Mondo Disease Ontology (MONDO:0007203), read 2026-09-29. CC BY 4.0.
Features
13 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Arteriovenous malformationHPOHP:0100026
- Very frequent (80% to 99% of cases)
- Bone painHPOHP:0002653
- Very frequent (80% to 99% of cases)
- Cavernous hemangiomaHPOHP:0001048
- Very frequent (80% to 99% of cases)
- Prolonged bleeding timeHPOHP:0003010
- Very frequent (80% to 99% of cases)
- Skin rashHPOHP:0000988
- Very frequent (80% to 99% of cases)
- Visceral angiomatosisHPOHP:0100761
- Very frequent (80% to 99% of cases)
- Abnormality of coagulationHPOHP:0001928
- Frequent (30% to 79% of cases)
- Abnormality of the vasculatureHPOHP:0002597
- Frequent (30% to 79% of cases)
- Intestinal bleedingHPOHP:0002584
- Frequent (30% to 79% of cases)
- Subcutaneous noduleHPOHP:0001482
- Frequent (30% to 79% of cases)
- VolvulusHPOHP:0002580
- Frequent (30% to 79% of cases)
- Gastrointestinal infarctionsHPOHP:0005244
- Occasional (5% to 29% of cases)
Show the remaining 1
- Microcytic anemiaHPOHP:0001935
- Occasional (5% to 29% of cases)
Where it sits
Other names
4 names
Resolves to: blue rubber bleb nevus
- Also called
- bean syndromeBlue Rubber Bleb Nevus syndromeBRBNBRBNS