benign neonatal seizures
Findings
No curated finding names benign neonatal seizures yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare genetic epilepsy syndrome characterized by the occurrence of afebrile seizures in otherwise healthy newborns with onset in the first few days of life.
Definition from the Mondo Disease Ontology (MONDO:0016027), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Focal clonic seizureHPOHP:0002266
- Very frequent (80% to 99% of cases)
- Focal EEG discharges with secondary generalizationHPOHP:0011188
- Very frequent (80% to 99% of cases)
- Focal tonic seizureHPOHP:0011167
- Very frequent (80% to 99% of cases)
- Focal-onset seizureHPOHP:0007359
- Very frequent (80% to 99% of cases)
- Neonatal seizureHPOHP:0032807
- Very frequent (80% to 99% of cases)
- ApneaHPOHP:0002104
- Frequent (30% to 79% of cases)
- Circumoral cyanosisHPOHP:0032556
- Frequent (30% to 79% of cases)
- ClonusHPOHP:0002169
- Frequent (30% to 79% of cases)
- Focal autonomic seizureHPOHP:0011154
- Frequent (30% to 79% of cases)
- Generalized tonic seizureHPOHP:0010818
- Frequent (30% to 79% of cases)
- Limb myoclonusHPOHP:0045084
- Frequent (30% to 79% of cases)
- Axial hypotoniaHPOHP:0008936
- Occasional (5% to 29% of cases)
Show the remaining 5
- Facial ticsHPOHP:0011468
- Occasional (5% to 29% of cases)
- Gastroesophageal refluxHPOHP:0002020
- Occasional (5% to 29% of cases)
- Simple febrile seizureHPOHP:0011171
- Occasional (5% to 29% of cases)
- Increased theta frequency activity in EEGHPOHP:0031535
- Very rare (1% to 4% of cases)
- Status epilepticusHPOHP:0002133
- Very rare (1% to 4% of cases)
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
Other names
8 names
Resolves to: benign neonatal seizures
- Also called
- benign familal neonatal seizuresbenign familial convulsionbenign familial convulsionsbenign familial neonatal convulsionsbenign familial neonatal epilepsybenign familial neonatal seizuresBFNSseizures, benign familial neonatal