basal-like breast carcinoma
MONDO:0004984Mondo
Findings
No curated finding names basal-like breast carcinoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A biologic subset of breast carcinoma defined by high expression of genes characteristic of basal epithelial cells, including KRT5 and KRT17, annexin 8, CX3CL1, and TRIM29, and usually by lack of expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). It is the most common subtype of breast cancer associated with BRCA1 mutations, and is associated with a poor prognosis.
Definition from the Mondo Disease Ontology (MONDO:0004984), read 2026-09-29. CC BY 4.0.
Where it sits
Other names
2 names
Resolves to: basal-like breast carcinoma
- Also called
- basal-like breast cancerbasal-like subtype of breast carcinoma