Barrett esophagus
Findings
No curated finding names Barrett esophagus yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)
Definition from the Mondo Disease Ontology (MONDO:0013662), read 2026-09-29. CC BY 4.0.
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Esophageal ulcerationHPOHP:0004791
- Very frequent (80% to 99% of cases)
- Gastroesophageal refluxHPOHP:0002020
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
Other names
11 names
Resolves to: Barrett esophagus
- Also called
- Barrett esophagus/esophageal adenocarcinomaBarrett's esophagusBarrett's oesophagus with esophagitisBarrett's ulcer of oesophagusBECELLOCLEcolumnar epithelial-lined Lower esophaguscolumnar epithelial-lined Lower oesophaguscolumnar-lined esophaguscolumnar-lined oesophagus