autosomal dominant nonsyndromic hearing loss 51
Findings
No curated finding names autosomal dominant nonsyndromic hearing loss 51 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An autosomal dominant nonsyndromic deafness that is characterized by postlingual onset in the fourth decade of life with high frequency progressive hearing loss and has material basis in a 269-kb duplication of chromosome 9q21.11 involving the TJP2 and FAM189A2 genes.
Definition from the Mondo Disease Ontology (MONDO:0013305), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Progressive · Late young adult onset
HPO, annotations 2026-09-02
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Hearing impairmentHPOHP:0000365
Where it sits
Other names
1 name
Resolves to: autosomal dominant nonsyndromic hearing loss 51
- Also called
- chromosome 9q21.11 duplication syndrome