autoimmune thrombocytopenic purpura
MONDO:0008558Mondo
Findings
No curated finding names autoimmune thrombocytopenic purpura yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin.
Definition from the Mondo Disease Ontology (MONDO:0008558), read 2026-09-29. CC BY 4.0.
Features
20 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- ThrombocytopeniaHPOHP:0001873
- Very frequent (80% to 99% of cases)
- Anti-glutamic acid decarboxylase antibody positivityHPOHP:0025329
- Frequent (30% to 79% of cases)
- Anti-insulin antibody positivityHPOHP:0034062
- Frequent (30% to 79% of cases)
- Anti-islet antigen-2 antibody positivityHPOHP:0034063
- Frequent (30% to 79% of cases)
- Anti-platelet antigen antibody positivityHPOHP:4000170
- Frequent (30% to 79% of cases)
- Anti-thyroglobulin antibody positivityHPOHP:0032069
- Frequent (30% to 79% of cases)
- Anti-thyroid peroxidase antibody positivityHPOHP:0025379
- Frequent (30% to 79% of cases)
- Anti-thyroid-stimulating hormone receptor antibody positivityHPOHP:0034189
- Frequent (30% to 79% of cases)
- Arterial thrombosisHPOHP:0004420
- Frequent (30% to 79% of cases)
- Liver kidney microsome type 1 antibody positivityHPOHP:0030908
- Frequent (30% to 79% of cases)
- PetechiaeHPOHP:0000967
- Frequent (30% to 79% of cases)
- PurpuraHPOHP:0000979
- Frequent (30% to 79% of cases)
Show the remaining 8
- Abnormal vaginal bleedingHPOHP:0034263
- Occasional (5% to 29% of cases)
- Bruising susceptibilityHPOHP:0000978
- Occasional (5% to 29% of cases)
- EpistaxisHPOHP:0000421
- Occasional (5% to 29% of cases)
- Gastrointestinal hemorrhageHPOHP:0002239
- Occasional (5% to 29% of cases)
- Gingival bleedingHPOHP:0000225
- Occasional (5% to 29% of cases)
- HematuriaHPOHP:0000790
- Occasional (5% to 29% of cases)
Where it sits
Other names
5 names
Resolves to: autoimmune thrombocytopenic purpura
- Also called
- idiopathic thrombocytopeniaidiopathic thrombocytopenia purpuraidiopathic thrombocytopenic purpuraITPthrombocytopenic purpura, autoimmune