autoimmune polyendocrinopathy type 4
MONDO:0016423Mondo
Findings
No curated finding names autoimmune polyendocrinopathy type 4 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Features
28 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AutoimmunityHPOHP:0002960
- Obligate (100% of cases)
- Atrophic gastritisHPOHP:0002582
- Frequent (30% to 79% of cases)
- Autoimmune antibody positivityHPOHP:0030057
- Frequent (30% to 79% of cases)
- Celiac diseaseHPOHP:0002608
- Frequent (30% to 79% of cases)
- Macrocytic anemiaHPOHP:0001972
- Frequent (30% to 79% of cases)
- Type I diabetes mellitusHPOHP:0100651
- Frequent (30% to 79% of cases)
- AlopeciaHPOHP:0001596
- Occasional (5% to 29% of cases)
- Anterior pituitary dysgenesisHPOHP:0010625
- Occasional (5% to 29% of cases)
- Biliary cirrhosisHPOHP:0002613
- Occasional (5% to 29% of cases)
- Decreased circulating immunoglobulin concentrationHPOHP:0004313
- Occasional (5% to 29% of cases)
- Decreased total leukocyte countHPOHP:0001882
- Occasional (5% to 29% of cases)
- VitiligoHPOHP:0001045
- Occasional (5% to 29% of cases)
Reported absent (4)
- Graves diseaseHPOHP:0100647
- Hashimoto thyroiditisHPOHP:0000872
- Primary adrenal insufficiencyHPOHP:0008207
- Recurrent mucocutaneous candidiasisHPOHP:0002728
Show the remaining 16
- Abnormal blistering of the skinHPOHP:0008066
- Very rare (1% to 4% of cases)
- Abnormal pulmonary interstitial morphologyHPOHP:0006530
- Very rare (1% to 4% of cases)
- Antiphospholipid antibody positivityHPOHP:0003613
- Very rare (1% to 4% of cases)
- Aplasia/Hypoplasia of the spleenHPOHP:0010451
- Very rare (1% to 4% of cases)
- Autoimmune thrombocytopeniaHPOHP:0001973
- Very rare (1% to 4% of cases)
- Central diabetes insipidusHPOHP:0000863
- Very rare (1% to 4% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: autoimmune polyendocrinopathy type 4
- Also called
- APS type 4APS4autoimmune polyendocrine syndrome type 4autoimmune polyglandular syndrome type 4