autoimmune disease with susceptibility to mycobacterium tuberculosis
MONDO:0975847Mondo
Findings
No curated finding names autoimmune disease with susceptibility to mycobacterium tuberculosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Childhood onset
HPO, annotations 2026-09-02
Features
24 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Anti-insulin antibody positivityHPOHP:0034062
- 1 of 1 reported patient
- ArthritisHPOHP:0001369
- 1 of 1 reported patient
- Bone marrow hypocellularityHPOHP:0005528
- 1 of 1 reported patient
- Diffuse alveolar hemorrhageHPOHP:0025420
- 1 of 1 reported patient
- Extrapulmonary tuberculosisHPOHP:0032271
- 1 of 1 reported patient
- Ground-glass opacificationHPOHP:0025179
- 1 of 1 reported patient
- HepatomegalyHPOHP:0002240
- 1 of 1 reported patient
- HypothyroidismHPOHP:0000821
- 1 of 1 reported patient
- Immune dysregulationHPOHP:0002958
- 1 of 1 reported patient
- Increased circulating IgA concentrationHPOHP:0003261
- 1 of 1 reported patient
- Increased circulating IgG concentrationHPOHP:0003237
- 1 of 1 reported patient
- Peritoneal abscessHPOHP:0100592
- 1 of 1 reported patient
Show the remaining 12
- Positive bloodstream tuberculosis-induced T-cell-based interferon-gamma release assayHPOHP:6000901
- 1 of 1 reported patient
- Recurrent otitis mediaHPOHP:0000403
- 1 of 1 reported patient
- Respiratory failureHPOHP:0002878
- 1 of 1 reported patient
- SplenomegalyHPOHP:0001744
- 1 of 1 reported patient
- Type I diabetes mellitusHPOHP:0100651
- 1 of 1 reported patient
- VerrucaeHPOHP:0200043
- 1 of 1 reported patient
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- PDCD1HGNC:8760
- Limited · PanelApp Australia · Autosomal recessive · 2025
Where it sits
- A kind of