autism, susceptibility to, X-linked 2
Findings
No curated finding names autism, susceptibility to, X-linked 2 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A class of genetic disorders resulting in intellectual disability that is associated either with mutations of genes located on the X chromosome or aberrations in the structure of the X chromosome (sex chromosome aberrations).
Definition from the Mondo Disease Ontology (MONDO:0010341), read 2026-09-29. CC BY 4.0.
- Inheritance
- X-linked inheritance
HPO, annotations 2026-09-02
Features
4 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Mild intellectual disabilityHPOHP:0001256
- 5 of 7 reported patients
- Autistic behaviorHPOHP:0000729
- 4 of 10 reported patients
- PlagiocephalyHPOHP:0001357
- 2 of 5 reported patients
- SeizureHPOHP:0001250
- 1 of 8 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- NLGN4XHGNC:14287
- Strong · Ambry Genetics · X-linked · 2024
- Strong · Labcorp Genetics (formerly Invitae) · X-linked · 2021
- Strong · G2P · X-linked · 2024
- Strong · PanelApp Australia · X-linked · 2025
Where it sits
- A kind of
Other names
4 names
Resolves to: autism, susceptibility to, X-linked 2
- Also called
- autism susceptibility, X-linked 2, isolated cases, X-linkedautism, susceptibility to, X-linked type 2AUTSX2intellectual developmental disorder, X-linked, Isolated cases, X-linked