atrial septal defect
Findings
No curated finding names atrial septal defect yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Interauricular communication is a congenital malformation characterized by a communication between the atrial chambers of the heart.
Definition from the Mondo Disease Ontology (MONDO:0006664), read 2026-09-29. CC BY 4.0.
Features
19 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Atrial septal defectHPOHP:0001631
- Very frequent (80% to 99% of cases)
- Secundum atrial septal defectHPOHP:0001684
- Very frequent (80% to 99% of cases)
- Atrial fibrillationHPOHP:0005110
- Frequent (30% to 79% of cases)
- Systolic heart murmurHPOHP:0031664
- Frequent (30% to 79% of cases)
- Atrial flutterHPOHP:0004749
- Occasional (5% to 29% of cases)
- CardiomegalyHPOHP:0001640
- Occasional (5% to 29% of cases)
- Complete right bundle branch blockHPOHP:0011712
- Occasional (5% to 29% of cases)
- Congestive heart failureHPOHP:0001635
- Occasional (5% to 29% of cases)
- Exertional dyspneaHPOHP:0002875
- Occasional (5% to 29% of cases)
- FatigueHPOHP:0012378
- Occasional (5% to 29% of cases)
- PalpitationsHPOHP:0001962
- Occasional (5% to 29% of cases)
- Primum atrial septal defectHPOHP:0010445
- Occasional (5% to 29% of cases)
Show the remaining 7
- Pulmonary arterial hypertensionHPOHP:0002092
- Occasional (5% to 29% of cases)
- Recurrent respiratory infectionsHPOHP:0002205
- Occasional (5% to 29% of cases)
- Right axis deviationHPOHP:0033567
- Occasional (5% to 29% of cases)
- Right ventricular dilatationHPOHP:0005133
- Occasional (5% to 29% of cases)
- Sinus venosus atrial septal defectHPOHP:0011567
- Occasional (5% to 29% of cases)
- Coronary sinus atrial septal defectHPOHP:0011643
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- MYH6HGNC:7576
- Strong · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- Narrower terms (15)
- atrial septal defect 1
- atrial septal defect 2
- atrial septal defect 3
- atrial septal defect 4
- atrial septal defect 5
- atrial septal defect 6
- atrial septal defect 7
- atrial septal defect 8
- atrial septal defect 9
- atrial septal defect, coronary sinus type
- atrial septal defect, ostium primum type
- atrial septal defect, ostium secundum type
- atrial septal defect, sinus venosus type
- Lutembacher syndrome
- patent foramen ovale
Other names
7 names
Resolves to: atrial septal defect
- Also called
- ASDAtrial Septal Defectsatrial septum defectauricular septal defectcongenital atrial septal defectinteratrial septal defectinterauricular communication