aplasia of lacrimal and salivary glands
Findings
No curated finding names aplasia of lacrimal and salivary glands yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Aplasia of the lacrimal and salivary glands (ALSG) is a rare autosomal dominant disorder characterized by aplasia, atresia or hypoplasia of the lacrimal and salivary glands leading to varying features since infancy such as recurrent eye infections, irritable eyes, epiphora, xerostomia, dental caries, dental erosion and oral inflammation.
Definition from the Mondo Disease Ontology (MONDO:0008397), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- FGF10HGNC:3666
- Supportive · Orphanet · Autosomal dominant · 2021
Where it sits
- A kind of
Other names
2 names
Resolves to: aplasia of lacrimal and salivary glands
- Also called
- ALSGcongenital absence of lacrimal puncta and salivary glands