anonychia with flexural pigmentation
MONDO:0007131Mondo
Findings
No curated finding names anonychia with flexural pigmentation yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Anonychia with flexural pigmentation is characterized by anonychia and skin abnormalities (hyper- and hypopigmentation in axillae and groins, dry palmar and plantar skin leading to sore and cracked soles). It has been described in a mother and her two children. The mode of transmission is autosomal dominant.
Definition from the Mondo Disease Ontology (MONDO:0007131), read 2026-09-29. CC BY 4.0.
Features
13 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal hair morphologyHPOHP:0001595
- Very frequent (80% to 99% of cases)
- Abnormal nipple morphologyHPOHP:0004404
- Very frequent (80% to 99% of cases)
- Abnormal skin morphology of the palmHPOHP:0040211
- Very frequent (80% to 99% of cases)
- Abnormality of the plantar skin of footHPOHP:0100872
- Very frequent (80% to 99% of cases)
- Alopecia of scalpHPOHP:0002293
- Very frequent (80% to 99% of cases)
- AnonychiaHPOHP:0001798
- Very frequent (80% to 99% of cases)
- Axillary and groin hyperpigmentation and hypopigmentationHPOHP:0007471
- Very frequent (80% to 99% of cases)
- Carious teethHPOHP:0000670
- Very frequent (80% to 99% of cases)
- Convex nasal ridgeHPOHP:0000444
- Very frequent (80% to 99% of cases)
- Follicular hyperkeratosisHPOHP:0007502
- Very frequent (80% to 99% of cases)
- HyperkeratosisHPOHP:0000962
- Very frequent (80% to 99% of cases)
- Hypermelanotic maculeHPOHP:0001034
- Very frequent (80% to 99% of cases)
Show the remaining 1
- Macular telangiectasiaHPOHP:0030503
- Very frequent (80% to 99% of cases)
Where it sits
- A kind of